Avène Cicalfate+ Repairing Protective Cream
Avène Cicalfate+ Repairing Protective Cream is a multi-purpose repairing cream designed to soothe, protect and support the repair of sensitive and irritated skin. Suitable for the whole family from birth, this fragrance-free formula creates a protective film over irritated areas while helping restore the skin’s surface.
The formula combines C+-Restore™, Avène Thermal Spring Water, copper sulfate and zinc sulfate to provide repairing, soothing and purifying care. It is particularly useful when the skin feels uncomfortable, irritated or weakened by everyday external aggressors.
Avène reports that the cream helps promote epidermal repair from 48 hours, while its protective texture creates a “dressing effect” that shields the skin from further external stress.
What is Avène Cicalfate+ Repairing Protective Cream for?
Sensitive or irritated skin can become uncomfortable, red and more vulnerable to external factors. In these situations, the skin needs more than simple hydration: it can benefit from a product that helps protect the affected area while supporting the natural repair process.
Cicalfate+ Repairing Protective Cream provides three complementary actions:
- Repairs the epidermis and supports the skin’s natural recovery
- Soothes sensations of discomfort and irritation
- Purifies irritated areas by helping limit the risk of bacterial proliferation
The cream forms a protective layer over the skin, helping create a barrier against everyday external aggressors.
Key ingredients and their benefits
C+-Restore™
The formula contains C+-Restore™, a patented postbiotic repairing active derived from Avène Thermal Spring Water.
It supports epidermal repair and plays a central role in the Cicalfate+ formula. It is described as the first postbiotic repairing active ingredient derived from its Thermal Water.
Avène Thermal Spring Water
Avène Thermal Spring Water helps soothe sensitive and uncomfortable skin. Its inclusion complements the repairing action of C+-Restore™ and helps restore a feeling of comfort.
Copper and zinc sulfates
The combination of copper sulfate and zinc sulfate provides the formula with a purifying action. These ingredients help limit the risk of bacterial proliferation on irritated areas.
Together, the ingredients create a formula that combines repairing, soothing, protective and purifying care.
Who can use Cicalfate+ Repairing Protective Cream?
This versatile cream suits the whole family from 0 months of age.
It is particularly suitable for:
- Sensitive skin
- Irritated skin
- Superficial everyday irritations
- Dry or uncomfortable areas
- Skin that needs protective repairing care
- Adults, children and babies
The product can also provide external care for intimate areas, making it a useful multi-purpose product to keep at home.
For people undergoing or recovering from oncology treatments, skin can become particularly sensitive. However, specific use should follow the advice of the treating healthcare professional, especially when the skin shows significant damage or requires medical treatment.
A protective “dressing effect”
One of the distinctive features of Cicalfate+ Repairing Protective Cream is its protective texture.
The cream creates a film over the skin that helps protect irritated areas from external aggressors. This “dressing effect” makes it particularly practical for localised areas that need extra protection while they recover.
Despite its protective action, the cream remains easy to incorporate into everyday family skincare.
Clinically supported results
Avène reports the following results from clinical and laboratory testing:
- Helps repair irritated skin from 48 hours¹
- Provides a soothing effect from the first application¹
- Demonstrates 4x faster repair in an ex-vivo model compared with untreated skin³
The clinical study included 248 participants under dermatological, paediatric and gynaecological supervision, with the product applied twice daily.
These results support its role as a targeted repairing cream for superficial skin irritation.
How to use Avène Cicalfate+ Cream
Apply several times a day, whenever necessary.
Gently massage the cream onto the irritated area until evenly distributed.
For everyday minor irritations, apply a thin layer to clean, dry skin and repeat as needed.
Avène also recommends a simple soothing step for small everyday skin injuries: before applying Cicalfate+, you can use a compress with Avène Thermal Spring Water to help refresh and soothe the area.
Important advice
Cicalfate+ is intended for superficial, non-pathological skin irritations. If an area looks infected, becomes increasingly painful, shows significant inflammation or does not improve, seek appropriate medical advice rather than relying solely on cosmetic care.
A repairing routine for very dry and irritated hands
Hands often experience repeated exposure to water, cleansing products and environmental conditions. When they become very dry or irritated, a simple repairing routine can help.
- Dry and protect: Use Avène Cicalfate Drying Repair Spray when appropriate to help care for areas that require a drying step.
- Repair: Apply Avène Cicalfate+ Repairing Protective Cream to the affected areas several times a day.
For particularly dry hands, reapply after washing and whenever the skin starts to feel tight or uncomfortable.
Why choose Avène Cicalfate+ Repairing Protective Cream?
Avène Cicalfate+ Repairing Protective Cream is a practical multi-purpose treatment for sensitive and irritated skin. Its combination of C+-Restore™, Avène Thermal Spring Water, copper sulfate and zinc sulfate provides repairing, soothing and purifying care in one formula.
Its fragrance-free, protective texture makes it especially useful for families looking for a versatile product to keep available for everyday skin discomfort.
If you’re not sure whether Cicalfate+ is appropriate for a particular irritation, how to combine it with other repairing products, or which product from the Cicalfate+ range best suits your needs, contact us through the Lyskin Q&A section. Our team will be happy to provide personalised guidance.
Find more Avène products here.













Ava –
My holy-grail! I use it as not only a sos product but also as a face cream (at night) and I feel it really improves the quality of my skin. It is smooth, soft, and brighter.
I have acne-prone skin and this did not break me out at all!
I can’t recommend it enough!
Alexandra Marisa De Sousa Gonçalves –
Dear Ava,
Thank you so much for sharing your wonderful experience! We are truly delighted to hear that this product has become such an essential part of your skincare routine and that it has made your skin feel smoother, softer, and brighter.
It’s especially great to know that it works so well for your acne-prone skin without causing any breakouts. Your kind recommendation means a lot to us!
Thank you for trusting Lyskin. We’re always here to support you on your skincare journey!
Warm regards,
The Lyskin Team