ISDIN Ureadin Ultra30 Exfoliating Cream 100 ml – Intensive Care for Thickened, Callused Skin
ISDIN Ureadin Ultra30 Exfoliating Cream is an intensive exfoliating and moisturising treatment designed for very rough, thickened skin and areas prone to calluses. Formulated with 30% ISDIN Urea, it helps soften hardened skin, loosen accumulated dead skin cells and restore hydration. As a result, skin feels smoother, more flexible and more comfortable.
In addition, the formula contains lactic acid, allantoin and arginine to complement the exfoliating action of urea. Its rich yet non-greasy texture absorbs quickly, making it practical for targeted daily care.
Suitable for areas such as the feet, hands, elbows and knees, Ureadin Ultra30 is designed for skin that needs more intensive care than a standard body moisturiser can provide.
What is ISDIN Ureadin Ultra30 Exfoliating Cream used for?
Thickened skin can develop when dead skin cells accumulate on the surface. This process, known as hyperkeratosis, may occur in areas exposed to repeated pressure or friction, including the feet, hands, elbows and knees.
Although this thickening can act as a protective response, excessive build-up may leave the skin rough, hard or uncomfortable. Therefore, targeted care can help soften the affected areas while improving hydration.
Ureadin Ultra30 combines a high concentration of urea with exfoliating and skin-conditioning ingredients. More specifically, it helps to:
- Reduce thickened skin: Helps loosen accumulated dead skin cells and soften hardened areas.
- Smooth rough texture: Supports the reduction of visible scaling and roughness.
- Hydrate intensely: Helps attract and retain water in the skin.
- Support the skin barrier: Helps improve moisture retention and skin flexibility.
- Improve comfort: Softer, better-hydrated skin may feel less tight and uncomfortable.
Consequently, this cream is particularly suited to localised areas with pronounced thickening or callus-like build-up.
Main ingredients
30% ISDIN Urea
Urea is a component of the skin’s natural moisturising factor, which helps maintain hydration. At a concentration of 30%, it provides intensive moisturising benefits alongside a strong keratolytic action, helping loosen and remove accumulated dead skin cells.
Furthermore, urea helps soften thickened areas and improve skin flexibility. By combining exfoliation with moisture retention, it helps address both the rough texture and dryness commonly associated with hyperkeratosis.
Because of this high concentration, the cream is intended for targeted care of thickened skin rather than indiscriminate application to delicate or irritated areas.
Lactic acid
Lactic acid is an alpha-hydroxy acid (AHA) that helps exfoliate the skin’s surface and supports hydration. In addition, it contributes to improving the texture of rough skin by helping loosen accumulated dead skin cells.
Together with urea, it complements the formula’s exfoliating action. However, the combination may increase irritation on sensitive, damaged or inflamed skin.
Arginine
Arginine is an amino acid that helps condition the skin. It contributes to a softer skin feel and complements the moisturising components of the formula.
Allantoin
Allantoin is a skin-conditioning ingredient used to help maintain skin softness and comfort. In addition, it supports the care of rough skin by complementing the formula’s exfoliating and moisturising ingredients.
Who is ISDIN Ureadin Ultra30 recommended for?
Ureadin Ultra30 is intended for people with very thickened, rough or callused skin, particularly on the feet, hands, elbows and knees.
It may be useful when these areas need intensive exfoliation alongside hydration. Nevertheless, it is not suitable for every type of dry skin. Because the formula contains 30% urea and lactic acid, it may cause stinging or irritation when applied to sensitive, cracked or inflamed areas.
Important precautions:
- For external use only.
- Do not apply to irritated, damaged or broken skin.
- Avoid the spaces between the toes and fingers to help prevent skin maceration.
- Avoid contact with the eyes and mucous membranes.
- Keep out of reach of children.
If you have diabetes, reduced sensation in your feet or poor circulation, consult a healthcare professional before treating foot calluses yourself. Similarly, painful, bleeding or persistent thickened skin should be professionally assessed.
How to use ISDIN Ureadin Ultra30 Exfoliating Cream
Apply the cream twice daily to clean, dry skin, concentrating on the thickened areas and following the product packaging instructions.
- Clean the affected area gently.
- Dry the skin thoroughly, especially around the feet and between the toes.
- Apply a suitable amount of cream to the rough or thickened skin.
- Massage gently until absorbed, avoiding the interdigital spaces.
For best results, use it consistently as part of a targeted body-care routine. However, do not combine it with other strong exfoliating treatments on the same area unless advised by a healthcare professional. If persistent burning, redness or irritation occurs, discontinue use.
Clinical results and reported benefits
According to the supplied product information, clinical research presented at the 64th American Academy of Dermatology meeting in San Francisco in 2006 evaluated a 30% urea cream for hyperkeratotic skin conditions.
The reported results included:
- 75% increase in hydration, according to the cited product information.
- 61% reduction in itching, as reported in the supplied results.
- 40% reduction in skin thickness, according to the product information.
- 59% reduction in scaling, as reported in the cited study summary.
The supplied information also describes reductions in redness and water loss. These results relate to the specific study and assessment methods; therefore, they should not be interpreted as guaranteed outcomes for every user. Individual results may vary according to the severity of skin thickening, application consistency and skin tolerance.
Why choose ISDIN Ureadin Ultra30 Exfoliating Cream?
ISDIN Ureadin Ultra30 offers targeted care for skin affected by marked roughness, thickening and callus-like build-up. Its 30% urea concentration helps soften hardened skin while improving hydration, and lactic acid complements its exfoliating action.
Furthermore, arginine and allantoin contribute to skin conditioning. With its rich yet non-greasy texture, the cream is designed for practical application to areas that need more intensive care.
Looking for help with rough or callused skin? The right treatment depends on the location, degree of thickening and condition of your skin. If you are unsure whether a high-concentration urea cream is appropriate, ask a pharmacist or healthcare professional for personalised advice.
Find more Isdin products here.









Reviews
There are no reviews yet