Bioderma Sensibio Defensive Serum – Advanced Soothing & Anti-Ageing Care for Sensitive Skin
Strengthen, protect and soothe sensitive skin daily
The Bioderma Sensibio Defensive Serum is a high-performance soothing and moisturising concentrate designed to combat inflamm-ageing—a key factor behind premature skin ageing caused by environmental aggressors such as pollution, stress, and UV exposure.
Developed specifically for sensitive and sensitised skin, this serum works both preventively and correctively, helping the skin defend itself while visibly improving signs of ageing such as fine lines, wrinkles, and loss of radiance.
What is inflamm-ageing and why does it matter?
Sensitive skin is more prone to chronic micro-inflammation triggered by external aggressors. Over time, this leads to:
- Premature wrinkles and fine lines
- Loss of skin radiance
- Weakened skin barrier
- Increased reactivity and discomfort
Sensibio Defensive Serum targets this cycle directly, helping to break the vicious loop of sensitivity and ageing while restoring balance and resilience.
Key benefits of Bioderma Sensibio Defensive Serum
Immediate and long-lasting soothing action
Calms the skin instantly while reducing sensitivity over time, improving daily comfort.
Powerful antioxidant protection
Helps protect against free radicals and environmental stressors, with 90% of users reporting protection against external aggressions.
Strengthens the skin barrier
Reinforces the skin’s natural defenses, making it more resistant to irritation and dehydration.
Anti-ageing efficacy
Visibly reduces the appearance of wrinkles and fine lines while restoring skin luminosity.
Deep and lasting hydration
Provides up to 24 hours of hydration, ensuring the skin remains soft, smooth, and comfortable.
Lightweight, high-tolerance formula
- Fast-absorbing texture
- Non-greasy, non-sticky finish
- Fragrance-free
- Suitable for daily use
Advanced DEFENSIVE TECHNOLOGY™
At the heart of this serum is the exclusive DEFENSIVE TECHNOLOGY™, developed by Bioderma to address the root causes of sensitive skin and premature ageing.
Protective antioxidant action
- Carnosine + Vitamin E help neutralize free radicals and protect against oxidative stress
Barrier-strengthening action
- Tetrapeptide-10 stimulates the production of key components of the skin barrier
- Fucose polymer enhances skin resistance and resilience
Double soothing mechanism
- Red sage polyphenols reduce inflammation and skin reactivity
- Fucose polymer provides immediate and long-term calming effects
Together, these actives help restore the skin’s ability to defend itself, reducing sensitivity and slowing visible ageing.
How to use Sensibio Defensive Serum
For optimal results, integrate into your daily routine:
- Cleanse your skin with a gentle Sensibio cleanser
- Apply a few drops of the serum to face and neck
- Gently massage until fully absorbed
- Follow with your daily moisturizer
- Use morning and evening
- Suitable for daily use
Build a complete Sensibio routine
To maximize results, combine with other products from the Sensibio range:
- Cleanse with Sensibio Gel Moussant or Sensibio H2O
- Apply Sensibio Defensive Serum
- Follow with Sensibio Defensive Cream
- Protect with daily sunscreen in the morning
This routine helps maintain hydrated, soothed, and resilient skin.
Visible results you can expect
- Skin feels calmer and less reactive
- Improved protection against environmental stress
- Reduction in fine lines and wrinkles
- More radiant and even-looking complexion
- Long-lasting hydration and comfort
Need personalized advice?
At Lyskin Love Your Skin, we believe every skin is unique. If you have any questions about Bioderma Sensibio Defensive Serum or how to incorporate it into your routine, feel free to reach out via our Q&A section—our team is here to guide you.
Find more Bioderma products here.
How to use Sensibio Defensive Serum
For optimal results, integrate into your daily routine:- Cleanse your skin with a gentle Sensibio cleanser
- Apply a few drops of the serum to face and neck
- Gently massage until fully absorbed
- Follow with your daily moisturizer
- Use morning and evening
- Suitable for daily use
Ingredients (INCI):
Aqua/Water/Eau, Glycerin, Butylene Glycol, C15-19 Alkane, Squalane, Cellulose, C20-22 Alkyl Phosphate, C20-22 Alcohols, Pentylene Glycol, 1,2-Hexanediol, Caprylyl Glycol, Carnosine, Polyacrylate Crosspolymer-6, Maltodextrin, Xanthan Gum, Mannitol, Xylitol, Tocopherol, Salvia Miltiorrhiza Root Extract, Rhamnose, Biosaccharide Gum-1, Citric Acid, Glycine Soja (Soybean) Oil, Hydrolyzed Hyaluronic Acid, Sodium Hydroxide, Palmitoyl Tetrapeptide-10.| Weight | 180 g |
|---|---|
| Dimensions | 10 × 4 × 4 cm |
| Capacity | 30ml |
| Main Ingredients | Hyaluronic Acid, Vitamin E, Carnosine |
| Manufacturer Information | BIODERMA, Naos France SAS, 75 Cours Albert Thomas, 69003 Lyon, France |
| GTIN | 3701129804995 |
| MPN | 7244343 |
Isla –
After using the Sensibio micellar water for years, I decided to try this serum. The experience is pleasant, offering a soft and comfortable sensation. My skin doesn’t tighten anymore, which is great.
I think it is an excellent option for those who, like me, have sensitive and dry skin.
Alexandra Marisa De Sousa Gonçalves –
Dear Isla,
Thank you so much for taking the time to share your experience! We’re so happy to hear that the serum has been a lovely addition to your skincare routine — especially after years of enjoying the Sensibio micellar water.
It’s wonderful to know your skin feels soft, comfortable, and no longer tight. That kind of relief is exactly what we hope to offer, particularly for sensitive and dry skin.
We truly appreciate your kind words and continued trust
Warmly,
The Lyskin Team
Lillian –
I love this serum, it is perfect for my sensitive skin. The formula is fantastic! It’s light and not sticky on the face, and it keeps my skin soft and moisturized all day long. I also noticed a slight improvement in the appearance of my fine lines and wrinkles.
I highly recommend this serum!
Alexandra Marisa De Sousa Gonçalves –
Dear Lillian,
Thank you so much for your wonderful words!
We’re truly delighted to know that this serum has been such a perfect match for your sensitive skin. It’s amazing to hear that you’re enjoying its light texture and the long-lasting hydration, and even seeing those beautiful improvements in your skin’s appearance!
Your recommendation means a lot to us. We’re so grateful for your trust and so happy to have you in the Lyskin family. ✨
With heartfelt thanks,
The Lyskin Team