ISDIN Isdinceutics Hyaluronic Moisture Refill Sensitive Skin 50g – Hydrating Face Cream Eco-Refill
ISDIN Isdinceutics Hyaluronic Moisture Refill Sensitive Skin is a refill format of the intensive moisturising face cream specially formulated for sensitive skin prone to redness and dehydration. Its lightweight, fast-absorbing texture helps replenish moisture while leaving the skin feeling soft, comfortable and refreshed.
Enriched with hyaluronic acid, niacinamide, provitamin B5 and a dedicated Redness Relief Complex, this daily moisturiser helps reduce the appearance of redness, support the skin barrier and improve the look of early signs of ageing. With 80% ingredients of natural origin, the formula combines daily hydration with soothing and antioxidant care. The refill format allows you to replenish your compatible original container rather than replace the entire product packaging.
Key Benefits of ISDIN Hyaluronic Moisture Refill Sensitive Skin
- Intensive hydration: Hyaluronic acid, glycerin and other moisturising ingredients help attract and retain moisture, leaving skin feeling soft and comfortable.
- Helps reduce the appearance of redness: The Redness Relief Complex is designed to soothe sensitive skin and improve the appearance of visible redness.
- Supports the skin barrier: Niacinamide and provitamin B5 help condition the skin and support its natural protective function.
- Helps calm skin discomfort: The formula is designed to help relieve sensations of itching and discomfort associated with sensitive skin.
- Antioxidant care: Vitamin E helps protect the skin against oxidative stress caused by environmental factors.
- Helps smooth early fine lines: Improved hydration helps soften the appearance of fine lines associated with dryness.
- Lightweight, fast-absorbing texture: Provides daily moisture without a heavy feel.
- 80% ingredients of natural origin: Combines moisturising and skin-conditioning ingredients in a formula designed for sensitive skin.
- Convenient eco-refill format: Replenishes the compatible original container, helping reduce the need to replace the complete packaging.
Key Ingredients
ISDIN Isdinceutics Hyaluronic Moisture Refill Sensitive Skin combines hydrating, soothing and antioxidant ingredients to care for sensitive skin prone to redness.
- Hyaluronic Acid (Sodium Hyaluronate and Hydrolyzed Hyaluronic Acid): Helps attract and retain moisture, improving skin hydration, softness and the appearance of fine lines caused by dryness.
- Niacinamide (Vitamin B3): Helps support the skin barrier, improve skin comfort and reduce the appearance of redness.
- Provitamin B5 (Panthenol): Helps moisturise and condition the skin while supporting its natural protective barrier.
- Vitamin E (Tocopherol and Tocopheryl Acetate): Provides antioxidant benefits and helps protect the skin against oxidative stress.
- 4-T-Butylcyclohexanol: A skin-conditioning ingredient included to help improve comfort in sensitive skin.
- Hydroxyphenyl Propamidobenzoic Acid: A soothing ingredient included to help relieve feelings of skin discomfort.
- Glycerin: A humectant that attracts and retains water to help maintain hydration.
- Trehalose and Urea: Help support the skin’s moisture balance and improve softness.
- Alteromonas Ferment Extract and Algin: Ingredients included in the formula’s moisturising and protective approach.
Clinical Results
According to ISDIN’s product studies, the following results were reported:
- +57% hydration after 2 hours: Measured following a single application in a study involving 24 women aged 18–70 with dry skin.
- 86% reduction in the sensation of itching: Reported in a four-week product-use evaluation involving 30 participants aged 25–45 with sensitive skin.
- 97% reported calmer, healthier-looking skin: Based on a subjective assessment after daily use for four weeks.
- 93% reported an immediate reduction in visible redness: Reported in the same four-week product-use evaluation.
These findings come from specific manufacturer studies and participant assessments. Individual results may vary. The hydration study was conducted separately from the sensitive-skin evaluation.
How to Use ISDIN Hyaluronic Moisture Refill Sensitive Skin
- Remove the empty refill from the original container.
- Insert the new refill into the compatible original container, following the packaging instructions.
- Cleanse your face and gently pat the skin dry.
- Apply the cream to your face, neck and décolletage.
- Massage gently until fully absorbed.
Use morning and evening as part of your daily skincare routine. In the morning, finish with a broad-spectrum sunscreen of at least SPF 30, preferably SPF 50, to help protect the skin against UV-related damage.
For a complete routine, apply your eye cream and serum before moisturising.
Who Is It Suitable For?
ISDIN Isdinceutics Hyaluronic Moisture Refill Sensitive Skin is designed for adults with sensitive skin, particularly those experiencing dehydration, visible redness or the first signs of ageing.
It may be particularly suitable for skin that:
- Is sensitive or prone to visible redness.
- Feels dry, tight or uncomfortable.
- Looks dull or shows fine lines associated with dehydration.
- Needs a lightweight daily moisturiser.
- Benefits from soothing and antioxidant care.
It is also a practical option for existing users of the original Hyaluronic Moisture Sensitive Skin cream who want to replenish their compatible container.
If redness is persistent, severe or accompanied by burning, swelling or other symptoms, seek advice from a healthcare professional to identify the cause.
Important Precautions
- For external use only.
- Avoid contact with the eyes and mucous membranes.
- Do not apply to irritated or damaged skin.
- For adult use only.
- Keep out of reach of children.
- Check the ingredient list if you have known sensitivities, as the formula contains fragrance.
- Discontinue use if irritation or an adverse reaction occurs.
- Check compatibility with your original container before inserting the refill.
Why Choose ISDIN Hyaluronic Moisture Refill Sensitive Skin?
ISDIN Isdinceutics Hyaluronic Moisture Refill Sensitive Skin combines hyaluronic acid, niacinamide, provitamin B5 and soothing ingredients to provide daily hydration for sensitive, redness-prone skin. Its lightweight texture helps maintain moisture, improve comfort and reduce the appearance of visible redness while supporting a smoother, more radiant-looking complexion.
With 80% ingredients of natural origin and a convenient refill format, it is a practical choice for continuing your skincare routine while reducing the need for replacement packaging.
Need help choosing the right moisturiser for sensitive skin? Send us your questions through the product page’s Q&A section at Lyskin Love Your Skin. Our team will be happy to help you find the most suitable products for your skincare routine.
Learn more about Isdin products here.









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