Avène Cicalfate+ Intensive Repairing Serum 30 ml
Avène Cicalfate+ Intensive Repairing Serum is a facial serum designed to repair, soothe and hydrate sensitive, fragile and irritated skin. It targets a weakened skin barrier and helps restore the skin’s natural repair mechanisms, making it an excellent choice when the complexion feels dry, tight, uncomfortable or particularly vulnerable to daily environmental stress.
Highly concentrated in Avène Thermal Spring Water, Pro-vitamin B5 and TRP-Regulin™, this lightweight serum provides intensive care while maintaining a high level of tolerance. The fragrance-free and alcohol-free formula contains 96% ingredients of natural origin and suits all skin types, including sensitive skin.
Avène reports that the serum can repair one month’s worth of accumulated skin damage in a single application, based on a clinical study, while continued use helps reinforce the skin barrier over time.
What is Avène Cicalfate+ Intensive Repairing Serum for?
Everyday exposure to environmental factors can gradually weaken the skin barrier. Cold weather, wind, dry air, cleansing, friction and other external stresses may leave the complexion feeling tight, dry or uncomfortable.
When the barrier becomes compromised, the skin may also look dull, uneven or irritated.
Cicalfate+ Intensive Repairing Serum addresses these concerns with a combination of repairing, soothing and hydrating ingredients. It helps:
- Support the repair of the skin barrier
- Restore the skin’s natural repair mechanisms
- Soothe feelings of tightness and discomfort
- Reduce the appearance of irritation
- Provide 24-hour hydration
- Reinforce the skin’s defences against everyday aggressors
- Leave the skin feeling softer, smoother and more comfortable
Key ingredients and their benefits
Avène Thermal Spring Water
The formula contains a high concentration of Avène Thermal Spring Water, an important part of Avène’s approach to sensitive-skin care. It helps support skin comfort and complements the serum’s soothing and repairing action.
Pro-vitamin B5
Also known as panthenol, Pro-vitamin B5 is a well-known moisturising ingredient. It helps maintain skin hydration and contributes to a more comfortable feeling when the skin feels dry or tight.
TRP-Regulin™
TRP-Regulin™ helps soothe sensations of discomfort associated with skin sensitivity. Avène highlights its role in reducing skin hypersensitivity and supporting a calmer, more comfortable complexion.
Together, these ingredients create a targeted formula for skin that needs more than simple hydration.
Who is Avène Cicalfate+ Intensive Repairing Serum suitable for?
This serum is particularly suitable for adults with sensitive, fragile or irritated skin.
Consider it when your skin feels:
- Dry or dehydrated
- Tight or uncomfortable
- Fragile or sensitised
- Irritated by daily environmental stress
- Dull or lacking comfort
- In need of barrier-supporting care
Its fragrance-free and alcohol-free formula makes it a practical choice for people who prefer a minimalist approach to sensitive-skin care.
The serum can also work as a short-term intensive treatment for one month, or as a supportive product whenever the skin barrier needs additional care.
A lightweight texture for everyday use
Despite its intensive repairing action, the serum has a fresh, milky-gel texture. It absorbs quickly and leaves a soft, velvety finish rather than a heavy or greasy feeling.
This makes it easy to incorporate into both morning and evening routines and allows you to follow it with your usual moisturiser.
How to use Avène Cicalfate+ Intensive Repairing Serum
Use the serum twice a day, morning and evening.
Using the pipette, apply a few drops to the face, neck and eye contour before your usual skincare products.
Avène recommends using the serum for one month as part of an intensive repairing routine, alongside your usual day cream.
Clinically supported results
Avène reports several benefits from clinical and instrumental testing:
- Repairs one month’s worth of damage after one application¹
- Helps restore the skin’s barrier-repair mechanisms²
- Provides an immediate soothing effect³
- Delivers 24-hour hydration⁴
- Helps reinforce the skin barrier over time
In addition, a consumer study reported a reduction in skin irritation after regular use over 21 days.
These results make the serum particularly interesting for people who want to combine barrier repair with hydration and soothing care, rather than using a conventional moisturising serum alone.
Complete your Cicalfate+ skincare routine
For particularly dry or compromised skin, pair the serum with a Cicalfate+ repairing moisturiser. The serum provides a lightweight first layer of intensive care, while a richer repairing cream can help reinforce the protective layer afterwards.
During the daytime, always finish your routine with an appropriate broad-spectrum sunscreen, especially when your skin feels sensitive or weakened.
Why choose Cicalfate+ Intensive Repairing Serum?
Avène Cicalfate+ Intensive Repairing Serum offers targeted care for skin that needs to recover from everyday stress. Its combination of Avène Thermal Spring Water, Pro-vitamin B5 and TRP-Regulin™ helps repair the skin barrier, soothe discomfort and maintain hydration.
With 96% ingredients of natural origin, a fragrance-free and alcohol-free formula, and a fresh milky-gel texture, it provides intensive care without feeling heavy on the skin.
If you’re unsure whether this serum is the right choice for your skin or want advice on combining it with other Cicalfate+ products, contact us through the Lyskin Q&A section. Our team can help you build a simple routine based on your skin’s needs.



















Maricela –
I am not sure where you are getting your information, but great topic.